Accountable Communities for Health (ACHs) are place-based initiatives in which community, clinical, and policy strategies are coordinated with the aim of improving health outcomes and controlling health care costs. The multi-sector nature of ACHs combines strategies addressing specific chronic diseases or other health conditions in a mutually reinforcing way. The framework provides a methodology or “road map” for communities, funders, or government agencies interested in conducting an evaluation of local ACH initiatives or understanding and interpreting the results of such an evaluation.